Efficacy of a sucrose-formulated recombinant factor VIII used for 22 surgical procedures in patients with severe haemophilia A

Autor:	I, Scharrer, H H, Brackmann, Y, Sultan, T, Abshire, C, Gazengel, M, Ragni, E, Gorina, E, Vosburgh, E, Kellermann
Rok vydání:	2000
Předmět:	Adult Male Sucrose Factor VIII Treatment Outcome Chemistry Pharmaceutical Acute Disease Blood Loss Surgical Humans Female Middle Aged Hemophilia A Recombinant Proteins
Zdroj:	Haemophilia : the official journal of the World Federation of Hemophilia. 6(6)
ISSN:	1351-8216
Popis:	A sucrose-formulated recombinant FVIII (rFVIII-SF) was investigated under clinical trial conditions during surgical procedures in previously treated patients (PTPs). Fifteen PTPs with severe haemophilia A (FVIIIor = 1%) underwent 22 surgical procedures. The procedures performed cover a spectrum from minor to major surgery. Haemostatic outcome was assessed by the investigators to be excellent in 16 procedures and good in the remaining six procedures. It is concluded that rFVIII-SF is efficacious and safe in severe haemophilia A patients undergoing minor or major surgery.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::7bd4bcded9fbaebe3038c92e9cdc9602 https://pubmed.ncbi.nlm.nih.gov/11122384 Zobrazit plný text záznamu Plný text