[Analysis of prognostic factors of non-small cell lung cancer in patients under 40 years of age]
| Autor: | Chun-hua, Xu, Li-ke, Yu, Yu, Zhang, Hai-yan, Xie, Ke-ke, Hao, Wei, Hu, Ning, Xia, Ping, Zhan |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Lung Neoplasms Adolescent Combined Modality Therapy Carcinoembryonic Antigen Survival Rate Young Adult Carcinoma Non-Small-Cell Lung Antineoplastic Combined Chemotherapy Protocols Humans Female Karnofsky Performance Status Pneumonectomy Follow-Up Studies Neoplasm Staging Proportional Hazards Models Retrospective Studies |
| Zdroj: | Zhonghua zhong liu za zhi [Chinese journal of oncology]. 34(9) |
| ISSN: | 0253-3766 |
| Popis: | To investigate the prognostic factors for non-small cell lung cancer(NSCLC)in patients under 40 years of age.The clinicopathological data of 148 young patients with NSCLC were retrospectively analyzed. Kaplan-Meier and Cox regression analyses were used to analyze the relationship between prognostic factors and survival time.The patients were followed-up for 6 - 148 months, and the follow-up rate was 100%. In the whole group, 122 patients died and 26 cases were surviving. The 1-, 3- and 5-year survival rates were 54.7%, 10.4% and 5.6%, respectively. The median survival time (MST) was 14.7 months. Kaplan-Meier analysis showed that Karnofsky performance status (KPS), clinical stage, treatment modality and serum CEA were related with prognosis (P0.05). Multivariate analysis indicated that KPS, clinical stage, treatment modality and serum CEA were independent prognostic factors (P0.05).KPS, CEA, clinical stage and treatment modalities are independent prognostic factors in young NSCLC patients. |
| Databáze: | OpenAIRE |
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