Identification of a Bromodomain-containing Protein 2

Autor: Dong Ju, Lee, Jung Hye, Hwang, Jeongim, Ha, Go Eun, Yu, Seulgi, Kwon, Da Hye, Park, Deok Gyeong, Kang, Tae Wan, Kim, Hwa Chun, Park, Sang Mi, An, Chul Wook, Kim
Rok vydání: 2017
Předmět:
Zdroj: Korean Journal for Food Science of Animal Resources
ISSN: 1225-8563
Popis: Bromodomain-containing protein 2 (BRD2) is a nuclear serine/threonine kinase involved in transcriptional regulation. We investigated the expression and association of the BRD2 gene as a candidate gene for meat quality traits in Berkshire pigs. BRD2 mRNA was expressed at relatively high levels in muscle tissue. Statistical analysis revealed that the c.1709G>C polymorphism of the BRD2 gene was significantly associated with carcass weight, meat color (a*, redness), protein content, cooking loss, water-holding capacity, carcass temperatures 4, 12 and 24 h postmortem, and the 24 h postmortem pH in 384 Berkshire pigs. Therefore, this polymorphism in the porcine BRD2 gene may be used as a candidate genetic marker to improve meat quality traits in pigs.
Databáze: OpenAIRE