| Autor: |
L J, Wilson, R T, Horvat, L, Tilzer, A M, Meis, L, Montag, M, Huntrakoon |
| Rok vydání: |
1992 |
| Předmět: |
|
| Zdroj: |
Diagnostic molecular pathology : the American journal of surgical pathology, part B. 1(4) |
| ISSN: |
1052-9551 |
| Popis: |
A patient with chronic renal failure received a closely matched cadaveric kidney. Approximately 3 months after transplantation, the patient developed a metastatic malignant melanoma. A large retroperitoneal mass consisting of large pleomorphic polygonal neoplastic cells was found close to the donated kidney. This tumor was diagnosed as a malignant melanoma. DNA analysis of this tumor, the donated kidney, and the recipient indicated that the melanoma originated from the donor. Although this is not the first report of a donated melanoma, it is the first report of definitive DNA analysis of the origin of the malignant cells. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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