| Autor: |
Miguel González-Carbajal, Pascual, Mónica, Zayas Berbes, Milagros, Sáez Baños, María del Rosario, Abreu Vázquez, Ludmila, Martínez Leyva |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Acta gastroenterologica Latinoamericana. 41(3) |
| ISSN: |
0300-9033 |
| Popis: |
Medications to relief pain are more common in the everyday use during the colonoscopy practice, although schemes of medications vary.To evaluate the efficacy and the safety of propofol versus midazolam and petidhine in colonoscopy.A randomized and simple-blind controlled clinical trial was carried out. We included 512 patients who underwent a colonoscopy during the period from February 2008 to January 2009. using propofol in one group and midazolam plus petidhine in another.Cecal intubation was achieved in 247 patients (96.5%) with propofol and in 256 patients (100%) with midazolam plus petidhine. There were no significant differences between both methods regarding to the explored colon distance. Fifty-five patients (21.5%) had complications in the group receiving midazolam plus petidhine and 3 (1.2%) in the group receiving propofol. Complications were mild in both groups. Propofol reduced the relative risk of complications in 94.6% and absolute risk in 20.3%. Patients referred the same satisfaction degree with both methods.The use of propofol and midazolam plus petidhine is equally efficacious in the performance of the colonoscopy, while propofol is safer than midazolam plus propofol as a method of deep sedation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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