Neuroprotective effect of standardized extracts of three

Autor: Jai, Malik, Supreet, Kaur, Maninder, Karan, Sunayna, Choudhary
Rok vydání: 2020
Předmět:
Zdroj: Nutritional neuroscience. 25(6)
ISSN: 1476-8305
Popis: The study was aimed to evaluate the efficacy of three commonly consumedEthanol extracts of leaves of three LS varieties were prepared, and standardized on the basis of quercetin content using HPLC. These extracts (100 and 200 mg kg,3-NP elicit marked deterioration in motor coordination, locomotor activity and memory in comparison to control group. Standardized ethanol extract of grand rapid (200 mg/kg) exhibited maximum activity amongst the three tested varieties. Therefore, its fractions were also evaluated, andThe results exhibit that LS (Grand rapid variety) prophylaxis mitigated 3-NP induced neurotoxicity and HD like symptoms in rats due to its potent antioxidant potential.
Databáze: OpenAIRE