| Autor: |
Yuu, Miyazaki, Atsuhiko, Ichimura, Ryo, Kitayama, Naoki, Okamoto, Tomoki, Yasue, Feng, Liu, Takaaki, Kawabe, Hiroki, Nagatomo, Yohei, Ueda, Ichiro, Yamauchi, Takuro, Hakata, Kazumasa, Nakao, Sho, Kakizawa, Miyuki, Nishi, Yasuo, Mori, Haruhiko, Akiyama, Kazuwa, Nakao, Hiroshi, Takeshima |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
eLife. 11 |
| ISSN: |
2050-084X |
| Popis: |
The growth plates are cartilage tissues found at both ends of developing bones, and vital proliferation and differentiation of growth plate chondrocytes are primarily responsible for bone growth. C-type natriuretic peptide (CNP) stimulates bone growth by activating natriuretic peptide receptor 2 (NPR2) which is equipped with guanylate cyclase on the cytoplasmic side, but its signaling pathway is unclear in growth plate chondrocytes. We previously reported that transient receptor potential melastatin-like 7 (TRPM7) channels mediate intermissive Ca |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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