| Autor: |
J F, Quarleri, B H, Robertson, V, Mathet, S D, Sinha, I, Badía, B, Frider, A, Ferro, C, Galoppo, S, Sookoian, G, Castaño, J R, Oubiã |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
Medicina. 58(2) |
| ISSN: |
0025-7680 |
| Popis: |
HCV genomic characterization was performed by nucleotide sequence analysis (n=50) combined with restriction fragment length polymorphism (RFLP) of the 5' UTR region in 82 isolates corresponding to different Argentine groups. Genotype 1 was detected in 70.7% of the samples (58 out of 82), genotype 2 in 21.9% (18 of 82) and genotype 3 in the remaining 6 sera (7.3%). HCV 1b subtype contributed with 35.3% to the whole population studied (29 to 82) and was detected in 6 out of 21 sporadic cases. Besides their epidemiological significance, these results should be taken into account when future vaccines are considered on the basis of geographical HCV genotypic prevalence. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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