| Autor: |
M, Schmitt, O K, Mohrs, S E, Petersen, K F, Kreitner, T, Voigtländer, T, Wittlinger, G, Horstick, S, Ziegler, J, Meyer, M, Thelen, W G, Schreiber |
| Jazyk: |
němčina |
| Rok vydání: |
2002 |
| Předmět: |
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| Zdroj: |
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 174(2) |
| ISSN: |
1438-9029 |
| Popis: |
Comparison between two semiquantitative methods and a quantitative evaluation of myocardial blood flow (MBF) for assessment of myocardial perfusion reserve (MPR) in patients with CAD.9 patients with coronary stenoses50 % were examined with an ECG-gated Saturation Recovery Turbo FLASH sequence by using Gd-DTPA as contrast agent (CA). The entive measurements were performed both during rest and hyperemia induced by adenosine. The up-slopes of the signal-time S(t) curves in the myocardium and left ventricular (LV) cavity were evaluated by a linear fit. MPR was calculated from the original up-slopes of the myocardial S(t) curves and from the up-slopes, which were normalized to the up-slopes of the LV S(t) curves, respectively. For quantification of MBF values, the mathematical model MMID 4 was used and MPR was evaluated from the MBF values.With all tested methods, MPR was reduced in myocardial regions subtended by arteries with stenoses/= 70 % compared with remote regions. With MMID 4 and the normalized up-slope method, differences between severe ischemic and remote regions were statistically significant.The up-slope method with normalization and quantification with MMID 4 are more sensitive methods to differentiate between remote and ischemic myocardium than the up-slope method without normalization. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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