The influence of 1-10 kD fraction from brains of the hibernating ground squirrel and the Yakut horse on proliferation and protein synthesizing system of Ehrlich ascitic carcinoma cells

Autor:	A K, Gulevsky, V I, Grischenko, O S, Tereschenko, I J, Shchenyavcky
Rok vydání:	2009
Předmět:	Brain Proteins Sciuridae DNA Adaptation Physiological Cold Temperature Protein Subunits Hibernation Animals RNA Horses Carcinoma Ehrlich Tumor Peptides Cell Proliferation
Zdroj:	Cryo letters. 26(5)
ISSN:	0143-2044
Popis:	The experimental data presented in the work testify to the cytostatic activity of 1-10 kD polypeptide fractions from brains of the hibernating ground squirrel and the Yakut horse towards Ehrlich ascitic carcinoma (EAC) cells. The experiments on the investigation of the inhibiting influence of 1-10 kD fractions from tissues of the hibernating and cold-adapted animals on protein-synthesizing system of EAC cells allow us to conclude that the cytostatic effect of the fractions is effected at the genetic level in the tumor cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::7a31d53bb720bc493975c290466189d3 https://pubmed.ncbi.nlm.nih.gov/19827243 Zobrazit plný text záznamu