| Autor: |
J F, Hollis, S, Satterfield, F, Smith, M, Fouad, P S, Allender, N, Borhani, J, Charleston, M, Hirlinger, N, King, R, Schultz |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Annals of epidemiology. 5(2) |
| ISSN: |
1047-2797 |
| Popis: |
Phase II of the Trials of Hypertension Prevention is a multicenter, randomized, controlled trial designed to determine the efficacy of weight loss and reduction of sodium intake for lowering blood pressure and incidence of hypertension among persons with high-normal levels of blood pressure. The 2 x 2 factorial study design includes weight loss alone, restricted sodium intake alone, the combination of weight loss and sodium restriction, and a control group. Nine clinical centers used a variety of recruitment strategies to enroll 2382 participants over 17 months, which exceeded the sample size goal of 2250. Among randomized participants, 21% were minorities and 34% were women. Overall, direct mail generated the most randomized participants (73%), followed by community screening (12%) and media advertisement (11%). Referrals from community health care providers yielded few participants. Prescreening improved overall efficiency and reduced costs. Participants who were more likely to drop out voluntarily during the three-visit screening regimen tended to be younger, single, male, smokers, and less educated. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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