| Autor: |
Nthai E, Ramoshaba, Hugo W, Huisman, Leandi, Lammertyn, Konstantin E, Kotliar, Aletta E, Schutte, Wayne, Smith |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Hypertension research : official journal of the Japanese Society of Hypertension. 43(11) |
| ISSN: |
1348-4214 |
| Popis: |
Masked hypertension is known to induce microvascular complications. However, it is unclear whether early microvascular changes are already occurring in young, otherwise healthy adults. We therefore investigated whether retinal microvascular calibers and acute responses to a flicker stimulus are related to masked hypertension. We used the baseline data of 889 participants aged 20-30 years who were taking part in the African Prospective study on the Early Detection and Identification of Cardiovascular Disease and Hypertension. Clinic and 24-h ambulatory blood pressure were measured. The central retinal artery equivalent (CRAE) and central retinal vein equivalent were calculated from fundus images, and retinal vessel dilation was determined in response to flicker light-induced provocation. A smaller CRAE was observed in those with masked hypertension vs. those with normotension (157.1 vs. 161.2 measuring units, P 0.001). In forward multivariable-adjusted regression analysis, only CRAE was negatively related to masked hypertension [adjusted R |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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