| Autor: |
W, Boddi, C, Nozzoli, C, Francois, A, Amorosi, S, Grifoni, A, Morettini, J, Olivotto, G, Berni |
| Rok vydání: |
1994 |
| Předmět: |
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| Zdroj: |
Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna. 9(1) |
| ISSN: |
0393-9340 |
| Popis: |
Parathyroid gland carcinoma is a rare cause of primary hyperparathyroidism. The authors discuss the case of a 56-year-old man who presented with hypercalcemia and multiple bone lesions suggestive of tumor metastases. Laboratory and radiological investigations revealed primary hyperparathyroidism in a patient with evidence of osteitis fibrosa cystica, sustained by carcinoma of a mediastinal parathyroid gland. Early titration of parathyroid hormone (PTH) levels in all patients with hypercalcemia of unclear cause is important for early diagnosis of cases that are tumor-sustained and prevention of the most severe complications. The role of immunostaining with anti-PTH antibodies in demonstrating parathyroid gland tissue in ectopic and/or non-functioning primary tumors, as well as metastases, is also discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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