| Autor: |
M, Müller, K, Neftel, M, Wälti, S, Hauser, J, Erni, S, Arrenbrecht |
| Jazyk: |
němčina |
| Rok vydání: |
1983 |
| Předmět: |
|
| Zdroj: |
Schweizerische medizinische Wochenschrift. 113(40) |
| ISSN: |
0036-7672 |
| Popis: |
Penicillin-G degradation products have been shown to inhibit in vitro myelopoiesis in a dose-dependent manner. Similar inhibition was seen with 6 semisynthetic penicillins and 2 cephalosporins. 50% inhibitory doses in vitro well matched total and daily doses given in vivo before neutropenia developed. These findings suggest a toxic rather than an immune-mediated pathogenesis for betalactam-induced neutropenia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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