Positive association between gastro-oesophageal reflux disease and irritable bowel syndrome in a Chinese population

Autor:	T K, Cheung, K F, Lam, W H C, Hu, C L K, Lam, W M, Wong, W M, Hui, K C, Lai, S K, Lam, B C Y, Wong
Rok vydání:	2007
Předmět:	Adult Male China Depressive Disorder Adolescent Age Factors Anxiety Middle Aged Irritable Bowel Syndrome Sex Factors Surveys and Questionnaires Gastroesophageal Reflux Prevalence Hong Kong Humans Female Sick Leave Aged
Zdroj:	Alimentary pharmacologytherapeutics. 25(9)
ISSN:	0269-2813
Popis:	Gastro-oesophageal reflux disease and irritable bowel syndrome are common diseases which may be related.To examine the association between gastro-oesophageal reflux disease and irritable bowel syndrome in Chinese population in Hong Kong.Randomly selected ethnic Chinese were invited to participate in a telephone survey in 1996. Gastro-oesophageal reflux disease was defined as subjects having heartburn and/or acid regurgitation once weekly or more. Irritable bowel syndrome was diagnosed according to the Rome I criteria. The association between gastro-oesophageal reflux disease and irritable bowel syndrome was calculated using a statistical model which allows the odds ratio to be measured.One thousand six hundred and forty-nine subjects completed the interview (response rate 62%). The population prevalence of gastro-oesophageal reflux disease and irritable bowel syndrome were 5% and 4%, respectively. Thirteen per cent of subjects with gastro-oesophageal reflux disease and 11% with irritable bowel syndrome suffered from both gastro-oesophageal reflux disease and irritable bowel syndrome. The OR of having gastro-oesophageal reflux disease and irritable bowel syndrome together was estimated to be 3 (95% CI: 1.05, 6.27) indicating a positive association between the two diseases. This association occurred predominantly in male subjects [OR = 9.3, (95% CI: 2.3, 26.2)] but not as strong in females [OR = 1.5, (95% CI: 0.3, 4.3)]. Younger subjects were statistically more prone to the two diseases.There is a positive association between gastro-oesophageal reflux disease and irritable bowel syndrome, and their association occurs predominantly in male subjects.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::78b90fc969551523bb487ca1fcbce16d https://pubmed.ncbi.nlm.nih.gov/17439511 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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