[Evaluation of rearrangement of immunoglobulin genes and T cell receptors in determining low numbers of leukemic in children with acute lymphoblastic leukemia]

Autor: W, Podraza, E, Osipowicz, K, Ptaszyński, J, Lubiński, J, Fydryk
Rok vydání: 1991
Předmět:
Zdroj: Polski tygodnik lekarski (Warsaw, Poland : 1960). 46(48-49)
ISSN: 0032-3756
Popis: The samples from blood and/or bone marrow were analysed in 7 children at the time of initial diagnosis or relapse and in 9 children with clinical and hematologic remission of ALL. Molecular genetic methods were more sensitive than morphologic ones in leukemic cells detection: 5 children in remission of ALL demonstrated gene rearrangements. Clinical significance of the presence of low numbers of leukemic cells in remissions is still unknown.
Databáze: OpenAIRE