Retrospective study of cardiovascular disease risk factors among a cohort of combat veterans with lower limb amputation
| Autor: | Vibha, Bhatnagar, Erin, Richard, Ted, Melcer, Jay, Walker, Michael, Galarneau |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Databases Factual Veterans Health Risk Assessment Amputation Surgical Risk Factors cardiovascular disease insulin resistance Prevalence Humans limb amputation Iraq War 2003-2011 expeditionary medical encounter database Retrospective Studies Original Research Metabolic Syndrome combat injury Afghan Campaign 2001 dyslipidemia Hemodynamics blood pressure Middle Aged Vascular System Injuries Prognosis Lipids United States United States Department of Veterans Affairs Lower Extremity Cardiovascular Diseases Female Biomarkers |
| Zdroj: | Vascular Health and Risk Management |
| ISSN: | 1178-2048 |
| Popis: | Introduction Previous studies have shown that veterans with lower limb amputation have a higher risk for cardiovascular disease (CVD) compared with population-based controls. American veterans who have served in Iraq and Afghanistan with lower limb amputation may be at a similarly higher risk. Patients and methods The Navel Health Research Center (NHRC) maintains the Expeditionary Medical Encounter Database (EMED) of military personnel who have sustained combat limb amputation or serious limb injury during the conflicts in Iraq and Afghanistan. Department of Veterans Affairs data from 2003 to April 2015 was used to analyze CVD risk factors in this cohort. Veterans with either unilateral (n=442) or bilateral (n=146) lower limb amputation were compared to those with serious lower limb trauma without amputation (n=184). Multivariate regression was used to measure associations between lower limb amputation and CVD risk factors over an average of 8 years of follow-up. Outcomes included mean arterial pressure (MAP), low-density lipoprotein, high-density lipoprotein (HDL), and serum triglycerides (TG). Results Compared with the limb injury group, those with unilateral lower limb amputation had significantly lower HDL (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|