| Autor: |
Sutatip, Pongcharoen, Kwansuda, Supalap |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
American journal of reproductive immunology (New York, N.Y. : 1989). 61(4) |
| ISSN: |
1600-0897 |
| Popis: |
JEG-3 choriocarcinoma cell line has previously been reported to express a receptor for interleukin (IL)-17. The involvement of IL-17 in the production of progesterone and human chorionic gonadotropin by placental trophoblast has not been investigated.The present study investigated the in vitro effect of IL-17 on progesterone and human chorionic gonadotropin (hCG) secretion by JEG-3 cells. Both hormones were quantified using enzyme-linked immunosorbent assays.The results showed that IL-17 significantly increased progesterone secretion at 6 (P0.001) and 24 (P0.01) hr, while this cytokine had no effect on hCG secretion.Interleukin-17 may regulate the function of JEG-3 cells through increased progesterone secretion. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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