Assessment of the functional capacity for intracellular death and phagocytosis of polymorphonuclear cells in healthy neonates

Autor: G, Del Rey-Pineda, M V, Gómez-González, F, Solórzano-Santos, J L, Arredondo-García
Rok vydání: 1997
Předmět:
Zdroj: Archives of medical research. 28(3)
ISSN: 0188-4409
Popis: The objective of this study was to assess the functional capacity for intracellular death (ID) and/or phagocytic index (PI) of polymorphonuclear cells of 24-h-old healthy newborns with respect to the PMN cells of adults using the same standard exogenous source of opsonins. The ID and PI techniques were standardized and 2-3 ml of blood were used. No differences were found in the percentages of ID, P, PI among the PMNs of the newborns and those of the adults: 43.95 +/- 15.70 vs. 44.56 +/- 8.43 for ID; 38.96 +/- 14.34 vs. 39.00 +/- 14.54 for P; 1.71 +/- 0.54 vs. 1.73 0.45 for PI, respectively. It was concluded that the PMNs of 24-h newborns have an ID, P, PI functionality comparable to adult PMNs; differences observed in PMN function in newborns may be due to humoral deficiencies (opsonins).
Databáze: OpenAIRE