Optimal

Autor: Orazio, Zoccarato, Roberta, Matheoud, Michela, Lecchi, Camilla, Scabbio, Marcassa, Claudio, Marco, Brambilla
Rok vydání: 2020
Předmět:
Zdroj: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 28(1)
ISSN: 1532-6551
Popis: This investigation used image data generated by an anthropomorphic phantom to determine the minimalA cardiac phantom with a simulated PD was imaged under different R using different gamma cameras and reconstruction algorithms. The residual activity from precedent stress administration was simulated by modeling effective half-times in each compartment of the phantom and assuming a delay of 3 hours between the stress and rest studies. The net contrast (NC) of the PD in the rest study was assessed for different R, PD positions and scanner/software combinations. The optimal R will be the one that minimize the NC in the rest images RESULTS: The activity concentration ratio R, the position of the PD and the scanner/software combinations were all main effects with a statistically significant impact on the NC, in decreasing order of relevance. The NC diminished significantly only for R values up to 2. No further improvement was observed for NC for R values above 2 and up to 3. NC was significantly higher in anteroseptal than in posterolateral positions of the PD and higher for solid-state cameras.A rest-stress activity concentration ratio R of 2 in single-day stress-first myocardial perfusion imaging is enough to achieve the maximum net contrast in the PD. This ratio should be used to optimize patient's radiation exposure.
Databáze: OpenAIRE