[Dose-dependent effect of mezaton on kidney and heart functions]

Autor:	L L, Branchevskĭ, Z S, Filinova
Rok vydání:	1986
Předmět:	Male Phenylephrine Dogs Dose-Response Relationship Drug Ranidae Animals Female Heart In Vitro Techniques Sympathomimetics Kidney Myocardial Contraction Stimulation Chemical
Zdroj:	Farmakologiia i toksikologiia. 49(6)
ISSN:	0014-8318
Popis:	In unanesthetized dogs within 20 min after intravenous administration of 0.05 mg/kg of mezaton an increase of diuresis, the rate of glomerular filtration, effective renal plasma flow, filtration fraction, sodium and potassium excretion by the kidneys was observed. The dose of 0.5 mg/kg of mezaton produced the opposite changes. In the experiments on frogs mezaton administration in a dose of 200 mg/kg exerted the positive inotropic effect.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::77783950f526b619133b0c6ba128616b https://pubmed.ncbi.nlm.nih.gov/3817149 Zobrazit plný text záznamu