| Popis: |
Human chorionic somatomammotropin (HCS) levels were studied in normal smoking and nonsmoking primiparous adolescent pregnancies. 136 teenagers, aged 12-18 years, were divided into groups: nonsmokers, deep, and shallow inhalers, long, and short puffers, high, and low tar, and high, and low nicotin. Shallow inhaling and low nicotine exposure patients were found to have a later age of menarche than did nonsmokers (13.2 vs. 12.3 years, p=.03). The mean body weight of the mothers who smoked was slightly less (61 gm) than that of nonsmoking mothers. Except for long puffers, overall, smokers had significantly lower HCS values throughout pregnancy than noosmokers (p = .48 high tar-p = .002 low tar). However, in the third trimester those with the lowest smoking exposures had the lowest HCS values and the heavier smokers had slightly higher mean values than nonsmokers. These data suggest that HCS production may be more sensitive to low tar and nicotine exposure with possible tolerance or even stimulation occurring in larger doses. |
