Osthole Exerts Inhibitory Effects on Hypoxic Colon Cancer Cells via EIF2[Formula: see text] Phosphorylation-mediated Apoptosis and Regulation of HIF-1[Formula: see text]

Autor:	Kui-Yuan, Peng, Tz-Chong, Chou
Rok vydání:	2022
Předmět:	Vascular Endothelial Growth Factor A Coumarins Colonic Neoplasms Eukaryotic Initiation Factor-2 Human Umbilical Vein Endothelial Cells Tumor Microenvironment Humans Apoptosis Phosphorylation Hypoxia-Inducible Factor 1 alpha Subunit Cell Hypoxia
Zdroj:	The American journal of Chinese medicine. 50(2)
ISSN:	1793-6853
Popis:	Hypoxic microenvironment and dysregulated endoplasmic reticulum stress/unfolded protein response (UPR) system are considered important factors that promote cancer progression. Although osthole extracted from
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::7722a9823cbfbc9424d193901d402301 https://pubmed.ncbi.nlm.nih.gov/35114913 Zobrazit plný text záznamu