Synthesis and antimicrobial activity of N-Mannich bases of 3-[N'-sulphadoximino] isatin and its methyl derivative

Autor:	Surendra, N, Pandeya, P, Yogeeswari, D S, Ram, G, Nath
Rok vydání:	1998
Předmět:	Isatin Mannich Bases Structure-Activity Relationship Bacteria Microbial Sensitivity Tests Anti-Bacterial Agents
Zdroj:	Bollettino chimico farmaceutico. 137(8)
ISSN:	0006-6648
Popis:	Schiff's bases of isatin and 5-methyl isatin with sulphadoxine and then its N-Mannich bases were synthesised and evaluated for their anti-microbial activity. The piperidonemethyl group improved the activity and most of the compounds were more potent than the pure drugs.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::76b16e01f4fd24afaf220d2bf180f038 https://pubmed.ncbi.nlm.nih.gov/9835147 Zobrazit plný text záznamu