| Autor: |
Meiyu, Yu, Xuejing, Gu, Yanzheng, Qu, Fuyou, Sun, Yanli, Li, Feng, Zhao, Hui, Xu |
| Rok vydání: |
2021 |
| Zdroj: |
Evidence-based complementary and alternative medicine : eCAM. 2022 |
| ISSN: |
1741-427X |
| Popis: |
Azithromycin (AZM) is one of the most common broad-spectrum antibiotics. However, drug resistance is increasing and combination therapy has attracted great attention. AZM is usually combined with traditional Chinese medicine (TCM) preparations with heat-clearing and detoxifying effects, including Kumu injection (KM) made fromThe present study aimed to investigate synergistic antimicrobial and anti-inflammatory activities of KM plus AZM with the aim of understanding the mechanism of clinical efficacy of combination regimens.Seven common bacterial clinical isolates and LPS-induced RAW 264.7 cells were used for assay ofKM-AZM combination synergistically inhibitsKM-AZM combination displayed synergistic antibacterial and anti-inflammatory effects beneficial to the therapeutic potential against bacterial infection. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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