A 14-membered macrolide and isocoumarin derivatives from the cultured lichen mycobionts of Graphis vestitoides

Autor: Duy Hoang, Le, Yukiko, Takenaka, Nobuo, Hamada, Hiromi, Miyawaki, Takao, Tanahashi
Rok vydání: 2012
Předmět:
Zdroj: Chemicalpharmaceutical bulletin. 61(3)
ISSN: 1347-5223
Popis: Spore-derived mycobionts of the crustose lichen Graphis vestitoides collected in Vietnam were cultivated on a malt-yeast extract medium supplemented with 10% sucrose. The investigation of their metabolites resulted in isolation of a novel 14-membered macrolide and a new isocoumarin, together with five known isocoumarin derivatives. Their structures were determined by spectroscopic and chemical means. This is the first instance of isolation of a 14-membered macrolide from a lichen mycobiont.
Databáze: OpenAIRE