| Autor: |
R L, Rasmusson, S, Wang, R C, Castellino, M J, Morales, H C, Strauss |
| Rok vydání: |
1997 |
| Předmět: |
|
| Zdroj: |
Advances in experimental medicine and biology. 430 |
| ISSN: |
0065-2598 |
| Popis: |
A recently discovered class of ancillary subunits has been shown to modify the inactivation properties of alpha-subunits belonging to the Kv1 family of potassium channels. One of these subunits, Kv beta 1.2, modifies intrinsic alpha-subunit C-type inactivation. N-type inactivation and open channel block have been proposed to increase the rate of development of C-type inactivation. We demonstrate here that Kv beta 1.2 has kinetic properties which are consistent with rapid open channel block. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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