| Autor: |
Ellen M B P, Reuling, Dwayne D, Naves, Johannes M A, Daniels, Chris, Dickhoff, Pim C, Kortman, Mark A M B, Broeckaert, Peter W, Plaisier, Erik, Thunnissen, Teodora, Radonic |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Virchows Archiv : an international journal of pathology. 480(3) |
| ISSN: |
1432-2307 |
| Popis: |
In the 2021 WHO thoracic tumors, gradation of lung carcinoids in biopsies is discouraged. We hypothesized that atypical carcinoid (AC) could be reliably diagnosed in larger preoperative biopsies. Biopsy-resection paired specimens of carcinoid patients were included, and definitive diagnosis was based on the resection specimen according to the WHO 2021 classification. A total of 64 biopsy-resection pairs (26 typical carcinoid (TC) (41%) and 38 AC (59%)) were analyzed. In 35 patients (55%), tumor classification between the biopsy and resection specimen was concordant (26 TC, 9 AC). The discordance in the remaining 29 biopsies (45%, 29 TC, 0 AC) was caused by misclassification of AC as TC. In biopsies measuring 4 mm |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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