The Nigerian I/CDC strain of Plasmodium ovale in chimpanzees

Autor: C L, Morris, J S, Sullivan, H M, McClure, E, Strobert, B B, Richardson, G G, Galland, I F, Goldman, W E, Collins
Rok vydání: 1996
Předmět:
Zdroj: The Journal of parasitology. 82(3)
ISSN: 0022-3395
Popis: The chimpanzee is the only animal host currently available that can support the development of the human malaria parasite Plasmodium ovale. Thirty-one infections with the Nigerian I/CDC strain were induced in splenectomized chimpanzees. Maximum parasite counts ranged from 1,240 to 127,224/microliters. Infections were transient and unpredictable. Anopheles stephensi, Anopheles gambiae, Anopheles freeborni, and Anopheles dirus mosquitoes were infected by feeding through parafilm membranes on heparinized blood containing gametocytes; each species supported development to sporozoites in the salivary glands. Mean oocyst counts per infected mosquito ranged from 1 to 85.1; 21.7% of infected lots of mosquitoes averaged20 oocysts per positive mosquito gut. One infection was induced via the bites of infected An. gambiae. The prepatent period was 16 days.
Databáze: OpenAIRE