[Cytological study of early embryonic mortality in laboratory mice]

Autor:	Kh Kh, Semenov, A M, Malashenko
Rok vydání:	1975
Předmět:	Chromosome Aberrations Male Time Factors Genotype Embryonic Development Mice Inbred Strains Mice Inbred C57BL Mice Mice Inbred AKR Mice Inbred DBA Pregnancy Animals Laboratory Embryo Loss Animals Hybridization Genetic Female Genes Lethal Fetal Death Thiotepa Genes Dominant
Zdroj:	Biulleten' eksperimental'noi biologii i meditsiny. 80(10)
ISSN:	0365-9615
Popis:	Early embryogenesis of laboratory mice was studied cytologically. Preimplantation embryonic mortality in mice of the strains DBA/21Y, C57BL/61Y, 101/HY and in the CBWA females crossed with the B6 males did not exceed 4--6%. Mice of the strain AKRIY served as an exception with 29.6% preimplantation embryonic mortality level. Investigation of the chemically-induced dominant lethals showed that coarse structural chromosomal damages arrested the cleavage and caused the death of the embryos before the implantation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::763463a236097bb454089c773949e2ca https://pubmed.ncbi.nlm.nih.gov/819058 Zobrazit plný text záznamu