The Periodontal Pathogen

Autor: Hongle, Wu, Wei, Qiu, Xiaofang, Zhu, Xiangfen, Li, Zhongcong, Xie, Isabel, Carreras, Alpaslan, Dedeoglu, Thomas, Van Dyke, Yiping W, Han, Nadeem, Karimbux, Qisheng, Tu, Lei, Cheng, Jake, Chen
Rok vydání: 2022
Zdroj: Frontiers in aging neuroscience. 14
ISSN: 1663-4365
Popis: Alzheimer's Disease (AD) is the most common form of dementia in older adults and has a devastating impact on the patient's quality of life, which creates a significant socio-economic burden for the affected individuals and their families. In recent years, studies have identified a relationship between periodontitis and AD. Periodontitis is an infectious/inflammatory disease that destroys the supporting periodontal structure leading to tooth loss. Dysbiosis of the oral microbiome plays a significant role in the onset and development of periodontitis exhibiting a shift to overgrowth of pathobionts in the normal microflora with increasing local inflammation.
Databáze: OpenAIRE