[Peri-operative anticoagulation with danaparoid for a patient with Budd-Chiari syndrome and heparin-induced thrombocytopenia]

Autor: M, Brémaud, E, De Maistre, E, Junke, A, Guerci, J-M, Lalot, D, Longrois, T, Lecompte, C, Meistelman
Jazyk: francouzština
Rok vydání: 2003
Předmět:
Zdroj: Annales francaises d'anesthesie et de reanimation. 23(1)
ISSN: 0750-7658
Popis: We report a case of Budd-Chiari syndrome revealing a polycythemia vera and complicated by heparin-induced thrombocytopenia. A surgical porto-caval shunt was inserted with danaparoid as anticoagulant during the peri-operative period. The doses of danaparoid were as follows: a continuous intravenous infusion of 200 U/h with a target between 0.5 et 0.8 U/ml antifactor Xa activity during the preoperative period, followed by 100 U/h with a target of 0.3 U/ml during the peroperative period; an increase in doses of danaparoid to 150 and 200 U/h with a target above 0.5 U/ml was used during the postoperative period. This case report is a rare situation of hypercoagulable state, in a surgical context, treated with danaparoid.
Databáze: OpenAIRE