| Autor: |
R, Reid, C H, van der Meyden, B J, Erasmus, H, Meyer, A M, Hamilton |
| Rok vydání: |
1992 |
| Předmět: |
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| Zdroj: |
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 81(9) |
| ISSN: |
0256-9574 |
| Popis: |
Four laboratory workers developed uveitis-chorioretinitis, associated with encephalitis in 3 cases. The retinitis was characterised by haemorrhages and areas of retinal oedema, most marked over the posterior polar regions, and was associated with exudative retinal detachments. The lesions progressed over weeks and showed a severe retinal arterial vasculopathy with arteriolar narrowing, ghost vessel formation and the development of optic atrophy. The picture in 2 of the patients resembled that of the acute retinal necrosis syndrome (ARN). Antibodies to African horsesickness (AHS) virus were detected. The serology for AHS virus was positive in all 4 patients as well as in 5 of 15 laboratory workers from the same facility who were clinically and ophthalmologically normal. This is to our knowledge the first description of subclinical and probable clinical neurotropic AHS virus infection in man. AHS is a hitherto-unrecognised possible cause of viral retinitis and the ARN syndrome. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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