[Study on the estrogen derivative marked by CdTe quantum dots]

Autor: Wen-Ying, Zhong, Cui, Zhang, Guo-Feng, Xu, Ming, Yan, Dan-Ke, Xu
Rok vydání: 2011
Předmět:
Zdroj: Guang pu xue yu guang pu fen xi = Guang pu. 31(8)
ISSN: 1000-0593
Popis: Water-soluble CdTe quantum dots (QDs) stabilized by thioglycolic acid (TGA) with high quantum yield were synthesized. And the small biomolecule 17beta-amino-estradiol was marked successfully by CdTe QDs. The analysis of UV-Vis spectroscopy, fluorescence spectroscopy, infrared spectroscopy and inverted microscope photographs showed that the surface carboxyl of CdTe quantum dots conjugated with the amino of 17beta-amino-estradiol through the activation of N-hydroxysuccinimide. 17beta-amino-estradiol marked by CdTe QDs successfully provided an experimental basis for new drug screening model.
Databáze: OpenAIRE