Epi-inositol is biochemically active in reversing lithium effects on cytidine monophosphorylphosphatidate (CMP-PA). Short communication

Autor:	M H, Richards, R H, Belmaker
Rok vydání:	1996
Předmět:	Isomerism Cricetinae Cytidine Monophosphate Animals Phosphatidic Acids CHO Cells Glycerophospholipids In Vitro Techniques Lithium Transfection Receptors Muscarinic Inositol Rats
Zdroj:	Journal of neural transmission (Vienna, Austria : 1996). 103(11)
ISSN:	0300-9564
Popis:	In CHOm3 cells and rat cerebral cortex slices, epi-inositol was less potent but as effective as myo-inositol in reversing carbachol/lithium-stimulated CMP-PA accumulation whereas L-chiro- and scyllo-inositol were less active or inactive. These results with the four inositol isomers in two tissues correlate exactly with their effects on lithium-pilocarpine induced seizures and suggest a common mechanism of action for biochemical and behavioural effects.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::751b32c9271cf58323aa64cad43a6c2a https://pubmed.ncbi.nlm.nih.gov/9013414 Zobrazit plný text záznamu Full text from SpringerLink