| Autor: |
Sanja, Bojic, Dean, Hallam, Nuno, Alcada, Ali, Ghareeb, Rachel, Queen, Sagoo, Pervinder, Harley, Buck, Aya, Amitai Lange, Gustavo, Figueiredo, Paul, Rooney, Miodrag, Stojkovic, Alex, Shortt, Francisco C, Figueiredo, Majlinda, Lako |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Stem cells (Dayton, Ohio). 36(11) |
| ISSN: |
1549-4918 |
| Popis: |
One of the main challenges in limbal stem cell (LSC) biology and transplantation is the lack of definitive cell surface markers which can be used to identify and enrich viable LSCs. In this study, expression of 361 cell surface proteins was assessed in ex vivo expanded limbal epithelial cells. One marker, CD200 was selected for further characterization based on expression in a small subset of limbal epithelial cells (2.25% ± 0.69%) and reduced expression through consecutive passaging and calcium induced differentiation. CD200 was localized to a small population of cells at the basal layer of the human and mouse limbal epithelium. CD200 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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