Activity of fluconazole against Candida albicans isolates from HIV+ patients in a digestive candidosis turkey model

Autor:	J, Reynes, M, Mallie, P, Ravisse, J M, Bastide
Rok vydání:	1992
Předmět:	Disease Models Animal Turkeys AIDS-Related Opportunistic Infections Candidiasis Oral Candida albicans Candidiasis Animals Humans Crop Avian Drug Resistance Microbial Female Microbial Sensitivity Tests Fluconazole
Zdroj:	Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology. 30(5)
ISSN:	0268-1218
Popis:	Fluconazole activity against four strains of Candida albicans (three isolates from AIDS patients and one azole-resistant isolate, NCPF 3363) was studied in a turkey crop infection model. Isolate NCPF 3363 showed confirmed azole resistance in vitro and in vivo. Two isolates from AIDS patients were susceptible to fluconazole in vitro and in vivo. The third isolate was resistant to fluconazole in vitro (MIC = 100 micrograms ml-1), insensitive to 2.5 mg kg-1 but sensitive in vivo to a 5 mg kg-1 daily dose.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::74ead3f9d11bcfb053981719edeae2b3 https://pubmed.ncbi.nlm.nih.gov/1469537 Zobrazit plný text záznamu