Effect of FSH on E

Autor: Hui, Zhao, Junbang, Ge, Juncai, Wei, Jie, Liu, Chen, Liu, Chiyuan, Ma, Xiaoe, Zhao, Qiang, Wei, Baohua, Ma
Rok vydání: 2019
Předmět:
Zdroj: Cellular signalling. 66
ISSN: 1873-3913
Popis: Mammalian oocyte restores meiosis can be stimulated by follicle-stimulating hormone (FSH) under normal physiological conditions. G-protein coupled receptor 30 (GPR30), an non-classical estrogen membrane receptor, has been widely reported in teleost oocyte maturation. However, it remains unknown whether GPR30 involves the role of FSH in mammalian cumulus expansion and oocyte maturation. Here, we used mouse cumulus-oocyte complexes (COCs) as a model to investigate how FSH affects the in vitro maturation of mouse oocytes mediated by 17β-estradiol (E
Databáze: OpenAIRE