Synovial sarcoma of the head and neck: chromosomal translation (X;18) as a diagnostic aid

Autor:	R A, Cihak, W M, Lydiatt, D D, Lydiatt, J A, Bridge
Rok vydání:	1997
Předmět:	Adult Leiomyosarcoma Male X Chromosome Skull Neoplasms Pharyngeal Neoplasms Translocation Genetic Parotid Neoplasms Diagnosis Differential Sarcoma Synovial Head and Neck Neoplasms Humans Chromosomes Human Pair 18 Aged
Zdroj:	Headneck. 19(6)
ISSN:	1043-3074
Popis:	Synovial sarcoma, a rare tumor in the head and neck, has been historically diagnosed by its characteristic biphasic histologic pattern. Monophasic variants exist which can be difficult to diagnose.Two cases of synovial sarcoma of the head and neck are presented. Both cases, cytogenetic analysis was performed using standard protocols.Both tumors demonstrated a chromosomal translocation, t(X;18)(p11.2;q11.2), which either made or confirmed the diagnosis.Synovial sarcoma contains a characteristic chromosomal translocation which is a useful diagnostic tool, especially when histologic studies are equivocal.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::74d8aef8b23de890018d6b08be1e3d16 https://pubmed.ncbi.nlm.nih.gov/9278765 Zobrazit plný text záznamu Plný text