In vivo induction of granulopoiesis in visceral yolk-sac cells by foetal hepatic factors

Autor:	M A, Anckaert, M, Symann
Rok vydání:	1983
Předmět:	Mice Inbred C3H Cell Count Cell Differentiation Rats Inbred Strains In Vitro Techniques Hematopoiesis Rats Colony-Forming Units Assay Diffusion Mice Liver Animals Female Cell Division Cells Cultured Granulocytes Yolk Sac
Zdroj:	Journal of embryology and experimental morphology. 73
ISSN:	0022-0752
Popis:	In order to evaluate the hypothetical activity of foetal hepatic factors on putative yolk-sac haemopoietic stem cells we used the Double Diffusion Chamber (DDC) techniqUe. The DDC were made of a regulator compartment, where foetal hepatic tissue was introduced and a test compartment where visceral yolk-sac cells were cultured. In this system a hepatic signal induced the yolk-sac stem cells to differentiate along the granulocytic pathway but did not stimulate yolk-sac CFUs growth. Contrary to CFUs originating from foetal liver or adult bone marrow, yolk-sac CFUs do not increase numerically in diffusion chamber culture.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::74881cc44b735f3c0ea0e49b8d2cdad1 https://pubmed.ncbi.nlm.nih.gov/6875467 Zobrazit plný text záznamu