[Acute diltiazem poisoning: kinetic and hemodynamics study]

Autor: A, Jaeger, P, Sauder, G, Bianchetti, J, Kopferschmitt, M, Dahlet, L, Tritsch, F, Flesch
Jazyk: francouzština
Rok vydání: 1990
Předmět:
Zdroj: Journal de toxicologie clinique et experimentale. 10(4)
ISSN: 0753-2830
Popis: The authors report three cases of diltiazem overdose with hypotension and atrio-ventricular conduction disturbances. Hemodynamic study in 2 cases showed a hyperkinetic state with a decrease of systemic vascular resistances. Diltiazem kinetics studied in 2 cases showed a plasma half life of 5.4 and 8.3 hours, a prolonged absorption until the 28th hours in one case. Treatment included gastric lavage, oral activated charcoal (2 cases), plasma expanders and in 2 cases vasopressors with alpha effects. All three patients recovered.
Databáze: OpenAIRE