[Interest of radiotherapy of rectal cancer with synchronous metastases]

Autor: H, Tournat, V, Vendrely, B, Cherciu, D, Smith, C, Laurent, M, Capdepont, G, Kantor, J P, Maire
Jazyk: francouzština
Rok vydání: 2007
Předmět:
Zdroj: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique. 12(5)
ISSN: 1278-3218
Popis: There is no consensus about the treatment of rectal tumour when there are synchronous metastases. The interest of radiotherapy is debated.Thirty-seven patients with rectal tumour and synchronous metastases were treated with radiotherapy first between September 1994 and December 2004. We analysed the tolerance, local control, resecability, overall survival of such a therapeutic strategy.The mean follow-up was 30 months. Twenty-four tumors were resecable for both the primary site and the metastases. Thirteen were unresecable at the time of diagnosis. Thirty-three patients were treated with radiochemotherapy, ten with radiotherapy alone. Eighty-six decimal five percent of them had no pelvic symptom six weeks after the treatment. Twenty-one rectal tumours were finally resected. The disease progressed in six cases during the radiotherapy. Surgery of the metastases was possible for 12 patients with tumour initially resecable.Radiochemotherapy is a "tolerable" treatment, in spite of more frequent urinary or digestive side-effects. But, if there is no surgery, palliative effect of radiotherapy is limited.
Databáze: OpenAIRE