| Autor: |
Feng-Feng, Chen, Lei, Li, Xiang-Dong, Chen, Cheng, Zhou, Da-Qing, Liao |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 50(1) |
| ISSN: |
1672-173X |
| Popis: |
To investigate the analgesic mechanism of xylazine by inhibiting the activation of hyperpolarized cyclic nucleotide-gated (HCN) ion channels.HCN subchannel 1 (HCN1) knockout mice (HCN1The results demonstrated that %MPE of the mechanical pain stimuli test and the thermal radiation stimuli test increased with the higher concentration of xylazine injected for both HCN1Xylazine showed better analgesic effect on HCN1 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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