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The aim of this study was to determine the level of exposure to polychlorinated biphenyls (PCBs) and selected heavy metals among fishermen via dietary intake of fish and other seafood from the eastern coast along the Straits of Malacca. This study determined the neurobehavioural performances (based on neurobehavioural core test battery scores) of the fishermen and evaluated the correlations between scores of neurobehavioural core test battery and exposure factors. Ninety fishermen participated in the study. The total fish intakes of the fishermen were measured using a set of food frequency questionnaires. The PCBs contents in the seafood samples ranged between 0.2 and 0.6 pg/g fresh sample. The concentrations of mercury (Hg), arsenic (As), cadmium (Cd), and lead (Pb) in the seafood samples were 1.1-5.4, 0.3-4.4, 0.6-36.1, and 0.02-0.3 μg/g fresh sample, respectively. The PCBs, Hg, As, Cd, and Pb exposures of the fishermen was estimated to be 2.8, 0.02, 4.5, 0.09, and 0.5 pg/kg body weight/day, respectively. PCB and heavy metal exposures through dietary intake of fish and seafood were within the tolerable daily limits. The results of neurobehavioural core test battery revealed that the neurobehavioural performances of the fishermen were not affected due to PCB and heavy metal intoxication. No correlations were found between the exposure and neurobehavioural performance among the fishermen. These data are useful for policy makers to assure the safety and quality of seafood in relation to sea pollution. Although the levels of exposure were low, periodic assessment of the quality of fish and fish products is required due to the polluted seawater.本研究的目的是根据渔民从马六甲海峡东海岸获取的鱼和其他海鲜的膳食摄入 量来确定其暴露于多氯联苯（PCBs）和选定的重金属的水平。这项研究探讨 了渔民们的神经行为表现（基于神经行为核心测试分），并评估该神经行为核 心测试成绩和暴露因素之间的相关性。九十渔民参与了这项研究。用食物频率 问卷测量渔民们的总鱼摄入量。海鲜样品多氯联苯的含量介于0.2 和0.6 pg/g 新鲜样品。海鲜样品中的汞、砷、镉和铅的浓度分别为1.1-5.4、0.3-4.4、0.6- 36.1 和0.02-0.3 μg/g 新鲜样品。渔民们的多氯联苯、汞（Hg）、砷（As）、 镉（Cd）和铅（Pb）暴露估计分别为2.8、0.02、4.5、0.09 和0.5 pg/kg 体重/ 天。渔民们每日多氯联苯和重金属通过鱼和海鲜膳食摄入的暴露量均在可接受 的限度内。他们的神经行为核心测试结果显示渔民们的神经行为表现不受多氯 联苯和重金属中毒的影响。渔民们的神经行为表现与该暴露没有相关性。这些 数据有利于政策制定者确保与海洋污染有关的海产品的安全和质量。虽然该暴 露水平较低，由于海水受到污染，定期评估鱼和鱼产品质量是必要。. |
