[cDNA cloning of three new homeobox-containing genes of Anf class from human, chicken and newt]
| Autor: | O V, Kazanskaia, G V, Ermakova, M, Pannese, E, Boncinelli, A G, Zaraĭskiĭ |
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| Rok vydání: | 1998 |
| Předmět: |
Homeodomain Proteins
DNA Complementary Sequence Homology Amino Acid Molecular Sequence Data Genes Homeobox Gene Expression Regulation Developmental Chick Embryo Xenopus Proteins Polymerase Chain Reaction Pleurodeles Species Specificity Ectoderm Animals Humans Amino Acid Sequence Cloning Molecular DNA Primers |
| Zdroj: | Bioorganicheskaia khimiia. 24(3) |
| ISSN: | 0132-3423 |
| Popis: | On the basis of the analysis of cDNA of three new homeobox-containing genes from human, chicken, and newt, a new class of homeobox genes Anf is characterized homologous to the Xanf-1 gene from Xenopus laevis, earlier cloned by us. These genes may be largely involved in the specification of embryonic subdivisions in the forebrain region of the embryo. The homeodomains of the proteins encoded by these genes differ greatly in the primary structure from all previously described homeobox genes. The high variability of the homeodomain sequences of the proteins of this class imply their rapid evolution. |
| Databáze: | OpenAIRE |
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