Addison's disease, adrenal autoantibodies and computerised adrenal tomography

Autor:	R J, Eason, M S, Croxson, M C, Perry, S D, Somerfield
Rok vydání:	1982
Předmět:	Adult Male Adolescent Adrenal Gland Diseases Calcinosis Middle Aged Polynesia Autoimmune Diseases Diagnosis Differential Addison Disease Adrenocorticotropic Hormone Fludrocortisone Adrenal Glands Humans Tuberculosis Female Child Tomography X-Ray Computed Aged Autoantibodies New Zealand
Zdroj:	The New Zealand medical journal. 95(714)
ISSN:	0028-8446 1971-1980
Popis:	The present study describes 53 patients with Addison's disease, who attended Auckland hospitals between 1971-1980, 32 of whom presented for the first time during this period, when the mean annual incidence of Addison's disease was 4.5 cases/million population, and the respective frequency of idiopathic (auto-immune) and tuberculous aetiologies was 92 percent and 4 percent for caucasians, but 25 percent and 63 percent for Polynesians. In addition, adrenal reserve was tested by ACTH stimulation in 20 clinically non-Addisonian patients in whom circulating adrenal antibodies had been incidentally demonstrated and present for periods of up to six years, and was normal in all cases. Such antibodies therefore lack functional disease specificity. The diagnostic value of CT adrenal scanning in illustrating the contrasting appearances between tuberculous and auto-immune adrenalitis is shown in four patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::730b0caedfd53d41f5dba23ac3f3c394 https://pubmed.ncbi.nlm.nih.gov/6290954 Zobrazit plný text záznamu