Ventilatory Parameters in Obstetric Patients With COVID-19 and Impact of Delivery: A Multicenter Prospective Cohort Study

Autor: Daniela N, Vasquez, Roberto, Giannoni, Adriana, Salvatierra, Karina, Cisneros, Diego, Lafosse, Fernanda, Escobar, Martín, Montenegro, Paula, Juárez, Lucía, Visani, Verónica, Mandich, Erika, Barrozo, Mariana, Kirschbaum, Andrea V, Das Neves, María F, Valenti, María C, Canseco, Ignacio, Romero, Pedro, Macharé, Ana K, Marquez, Eva, Rodriguez, Cristina, Palacio, Laura, Rapela, José M, Amillategui Scenna, Rossana, Nuñez, Sebastián, Torres, Miguel A, González, Lorena, Franconieri, Daniela, Nasner, Patricia, Okurzaty, Gustavo A, Plotnikow, Dante, Intile
Rok vydání: 2022
Zdroj: Chest.
ISSN: 1931-3543
Popis: Current evidence on obstetric patients requiring advanced ventilatory support and impact of delivery on ventilatory parameters is retrospective, scarce, and controversial.What are the ventilatory parameters for obstetric patients with COVID-19 and how does delivery impact them? What are the risk factors for invasive mechanical ventilation (IMV) and for maternal, fetal, and neonatal mortality?Prospective, multicenter, cohort study including pregnant and postpartum patients with COVID-19 requiring advanced ventilatory support in the ICU.Ninety-one patients were admitted to 21 ICUs at 29.2 ± 4.9 weeks; 63 patients (69%) had delivered. Maximal ventilatory support was as follows: IMV, 69 patients (76%); high-flow nasal cannula, 20 patients (22%); and noninvasive mechanical ventilation, 2 patients (2%). Sequential Organ Failure Assessment during the first 24 h (SOFAContrary to expectations, pregnant patient lung mechanics were similar to those of the general population with COVID-19 in the ICU. Delivery was induced mainly for maternal reasons, but did not change ventilatory parameters other than Pao
Databáze: OpenAIRE