| Autor: |
Khaled W, Kabbara, Timothy, Cannon, Arthur, Winer, Raymond C, Wadlow |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Oncology (Williston Park, N.Y.). 36(8) |
| ISSN: |
0890-9091 |
| Popis: |
Cholangiocarcinomas are an aggressive group of heterogeneous malignancies that affect over 210,000 individuals globally each year. Their incidence is rising, particularly in Western countries. Traditionally, cholangiocarcinomas are classified based on anatomic location of the tumor and are treated with similar cytotoxic chemotherapy despite significant molecular and genomic differences. With the rise of genetic and molecular sequencing, several driver mutations have been identified and targeted as novel therapeutic approaches. The most common genomic alterations include changes in |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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