| Autor: |
J, Kiss, T, Tisza, F D, Tóth, A, Horváth, A, Stumpf |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Acta microbiologica Hungarica. 40(2) |
| ISSN: |
0231-4622 |
| Popis: |
Cell and serum samples from 7 Hungarian patients with mycosis fungoides were examined for the presence of HTLV-I-related DNA sequences and antibodies recognizing HTLV-I antigens. DNA sequences distantly related to the proviral DNA of HTLV-I were shown by Southern blot hybridization in 3 patients. Serum samples from these patients contained antibodies reactive with the internal core polypeptides of HTLV-I and HTLV-II, but not with the env gene encoded type-specific HTLV antigens. Restriction enzyme analysis with EcoRI, PstI, BamHI and SacI revealed structural similarity of the provirus(es) integrated in the DNA of mycosis fungoides cells to HTLV-I but not to HTLV-II. Data suggest that these proviruses and HTLV-I are similar to each other along gag and pol regions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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