Primary and salvage laser surgery of 341 glottic cancers-Comparison of treatment outcomes between University Head Neck Tertiary Referral Center and Local Head Neck Department
| Autor: | Piotr, Winiarski, Artur, Lewandowski, Grażyna, Greczka, Jacek, Banaszewski, Hanna, Klimza, Małgorzata, Wierzbicka |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Glottis Databases Factual Laryngectomy Risk Assessment Disease-Free Survival Cohort Studies Hospitals University Tertiary Care Centers Humans Neoplasm Invasiveness Prospective Studies Laryngeal Neoplasms Aged Neoplasm Staging Proportional Hazards Models Salvage Therapy Chi-Square Distribution Laryngoscopy Middle Aged Prognosis Survival Analysis Female Laser Therapy Poland Neoplasm Recurrence Local |
| Zdroj: | Lasers in surgery and medicine. 50(4) |
| ISSN: | 1096-9101 |
| Popis: | The main goal was to compare the clinical data of patients with T1 and T2 glottic cancer treated with COUnified databases for the 7-year period January 2005-December 2011 were created to compare these two cohorts. The database contained 341 patients: 231 from the tertiary center and 110 from the local department, of which 298 (87%) were men, and 43 (13%) were women.Cordectomy type I-IV was performed in 250 (73%) patients, cordectomy type V-VI in 84 (25%) patients, and cordectomy enlarged to epiglottic petiole in 7 (2%) patients. Local recurrence was observed in 96 (28%) cases. Among these cases, 81 (87.5%) patients had salvage surgery: 43 re-cordectomy, 10 open partial laryngectomy, and 28 total laryngectomy. The outcomes for the whole cohort, Tertiary Referral Center and Local Department respectively were as follows: larynx preservation rate was 91.8%, 93.6%, and 88%; 3-year disease specific survival was 97.4%, 97.9%, and 93.3%; 3-year overall survival was 93.5%, 96.6%, and 85.5%; 5-year disease specific survival was 95.2%, 95.2%, and 96.3%; and 5-year overall survival was 84.5%, 88.7%, and 76%, respectively.Comparison of the cohorts showed that outcomes of primary treatment were similar but there were noticeable differences in salvage treatment efficacy, favoring patients from the Tertiary Referral Center. Lasers Surg. Med. 50:311-318, 2018. © 2017 Wiley Periodicals, Inc. |
| Databáze: | OpenAIRE |
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